This paper assesses the efficacy of Integrated Personnel Payroll and Information System (IPPIS) in addressing the problem of ghost workers in Nigeria. The issue of ghost workers has been a major problem in the Nigerian civil service over the years. Objective of this study is to determine the extent to which implementation of IPPIS addressed the problem of ghost workers in the Nigerian civil service. Both primary and secondary sources of data were used, and expo facto research method was utilized. The researchers conclude that introduction of IPPIS in Nigeria has helped to check abnormality and regularized the payment of employees’ entitlement and it has helped to reduce the number of ghost workers level in the government payroll. Also, IPPIS has led to improvement in reporting of ghost workers and reduction in personnel costs of government. The researchers recommend that government should ensure all the employees who are not captured under IPPIS platform are captured in order to wipe away ghost workers in Nigeria system. Also, any corrupt officer found guilty of any criminal offences relating to ghost workers should be sanctioned appropriately in order to serve as deterrent to others.