Malaria remains a critical global health challenge, disproportionately affecting low- and middle-income countries, particularly those in sub-Saharan Africa. Despite ongoing global and regional eradication efforts, the disease continues to cause significant morbidity and mortality, with children under five and pregnant women being the most vulnerable groups. Malaria is caused by Plasmodium parasites, transmitted through the bites of infected female Anopheles mosquitoes. In Nigeria, malaria is endemic, with year-round transmission and seasonal peaks during the rainy season when mosquito breeding intensifies. Beyond its direct health impact, malaria imposes a substantial socio-economic burden by reducing productivity, escalating healthcare costs, and overwhelming healthcare systems, especially in rural and peri-urban areas with limited access to quality care and inadequate public health education. Nigeria contributes significantly to the global malaria burden, accounting for a large share of cases and deaths in sub-Saharan Africa. The disease is implicated in approximately 25% of infant deaths and 11% of maternal deaths annually within the country. Addressing malaria requires strengthened prevention strategies, improved health education, and enhanced access to effective diagnosis and treatment, particularly among vulnerable populations.