This study examines the relationship between entrepreneurship development and employment generation in Nigeria, with specific focus on Kosofe Local Government Area of Lagos State. Adopting a descriptive survey research design, the study targets entrepreneurs operating small and medium scale enterprises, youths engaged in start-up ventures, informal sector traders, unemployed individuals seeking entrepreneurial opportunities, and officials of entrepreneurship development agencies, local government departments, and non governmental organizations involved in enterprise and youth empowerment. A sample size of 120 respondents was selected using stratified random sampling across major sub areas of Kosofe LGA, namely Ketu, Ojota, Mile 12, Alapere, and Agboyi. Data were collected through structured questionnaires complemented with secondary data from government publications, academic journals, and development agency reports.  Findings reveal a significant positive relationship between entrepreneurship development initiatives and employment generation in Nigeria, as respondents generally agreed that such initiatives have contributed to job creation and empowered individuals to become job creators. The study also found that entrepreneurship training significantly enhances youths’ employability and likelihood of self employment. However, perceptions regarding the effectiveness of government led entrepreneurship programs were mixed, suggesting the need for improved accessibility and impact at the community level.The study concludes that entrepreneurship development, particularly through targeted training and supportive policies, plays a vital role in addressing unemployment challenges in Nigeria. It therefore recommends increased investment in entrepreneurship education, access to finance, and supportive institutional frameworks to strengthen employment generation and sustainable economic development.