This study investigates the relationship between monetary policy and productivity growth in Nigeria from the period of 1990- 2024. The specific objective of the study is to examine the impact of monetary policy on productivity growth in Nigeria. The underlying theoretical framework for the study is based on endogenous growth theory. The data were obtained from Central Bank of Nigeria statistical bulletin and National Bureau of statistics. Monetary policy rate, treasury bill rate, cash reserve requirement, money supply was used to measured monetary policy and productivity growth was measured using aggregate productivity growth rate. Johansen cointegration test was estimated to examine the impact of monetary policy on productivity growth in Nigeria. The findings revealed that monetary policy had a negative impact on productivity growth but not statistically significant. The result showed that Treasury bill rate and money supply had a significant negative impact on productivity growth. Finally, the result revealed that cash reserve requirement had a significant positive impact on productivity growth in Nigeria. The study recommends that there is a need for government to adopt efficient monetary policy instruments, encourage trade openness and promote financial inclusion by expanding access to financial services.