The Fe(III), Ru(III), Co(II), Ni(II), Cu(II), Pd(II), Zn(II), Cd(II) and Hg(II) complexes of a Schiff base derived from 4-aminobenzene sulfonamide and furan-2-carbaldehyde (FMABS, Scheme:1) have been synthesized and structurally characterized by various physico-chemical data. The ligand acts as a neutral, bidentate one towards the metal ions coordinating through azomethine nitrogen and furan oxygen. The geometry and the bonding characteristics associated with the complexes have been deduced from relevant spectral data. All the complexes are coloured and stable towards air and moisture. Fe, Ru, Co and Cu complexes are paramagnetic while the remaining are diamagnetic. Consolidating all the data obtained, the Fe, Ru and Cu complexes have been assigned an octahedral geometry, Ni and Pd complexes, a square planar geometry and the Zn, Cd and Hg complexes, a tetrahedral geometry. Further, the ligand and the metal complexes have been screened for their antimicrobial activities against two gram positive bacterial strains Basillus Subtillus, Staphylococcus Aurus and two gram negative bacterial strains Escherichia coli, Salmonella typhi, and two fungal strains Aspergillus niger and Penicill ium rubrum by agar plate technique and the results are presented. Both the antibacterial and antifungal activities of the synthesized metal complexes have been found to be more as compared to those of the ligand.