The study examined the relationship between employee innovativeness and organizational sustainability in the manufacturing sector in Rivers State, and domiciled in Presidential Hotels, Port Harcourt. The study was guided by four specific objectives, four corresponding research questions, and four hypotheses formulated to direct the investigation. A quasi-experimental research design was adopted, with a target population of 143 respondents. Using the Taro Yamane formula, a sample size of 105 participants was determined for the study. In addition to primary data, secondary data were obtained from existing empirical and descriptive literature accessed through online databases, academic journals, and relevant textbooks. The collected data were presented using frequency distribution tables and percentages, while chi-square statistics were employed to analyse the data and test the formulated hypotheses. The findings evidenced a significant relationship between the dimensions and measures of employee innovativeness and organizational sustainability. The study concluded that there is a positive relationship between employee innovativeness and organizational sustainability in Presidential Hotels, Port Harcourt. Based on the findings of the study, the researcher recommended among others that management of Presidential Hotels, Port Harcourt should establish a supportive environment that encourages employees to share creative ideas without fear of criticism so as to enhance economic resilience; the Hotel should not only gather innovative suggestions but also create a structured system for evaluating, testing, and implementing feasible ideas so as to boost motivation, commitment, and continuous creative thinking.