The study was carried out to investigate curriculum implementation for entrepreneurship practice in agriculture for secondary schools in Rivers State: Principals’ view. Two research questions were answered by the study which was a descriptive survey design with a population of 40 school principals in Etche, Rivers State. A sample size of 30 principals were selected using the stratified proportionate sampling technique as respondents. The instrument for data collection was a 18- item questionnaire which was validated by three experts and it gave a reliability coefficient of 0.74 which was obtained using Cronbach Alpha method. The data collected were analyzed with mean and standard deviation. The results showed a positive output of competence for the curriculum implementer in use of agricultural science for entrepreneurship practice by secondary school students and use of the most appropriate methods in curriculum implementation except for the need that the curriculum implementer should get more training on ICT to boost capacities in its use. Based on the findings, the following recommendations were made that agricultural science curriculum implementer in secondary schools in Rivers State should maintain the present level of curriculum implementation competence in order to continue to produce desired entrepreneurship results in the learners, agricultural science curriculum implementer should make themselves available for training and retraining programmes on ICT use, project teaching method produced the highest result when used by the curriculum implementer, thus, principals should encourage such for the curriculum implementer for building the three domains of learning, learners should avail themselves of every opportunity that may be presented by the teachers to enable them convert knowledge to practical skills, the government and other education stakeholders should help in the provision of facilities that develop entrepreneurship skills in secondary school agricultural science learners.