The study of objective was to determine the level of stress and burnout among fine and applied arts students in state colleges of education in south-east, Nigeria. Cross-sectional study was carried involving 500 fine and applied arts students from the study area through the application of multistage procedure. Perceive Stress Questionnaire (PSQ) was employed for data collection. Cronbach alpha was used to establish the study reliability which gave 0.91. Direct delivery of the questionnaire was employed to gather data with the aid of five research assistants. Mean, standard deviation and t-test was employed for data analysis. Probability level of 0.05 was used to test the study hypothesis. The result revealed that there is stress and burnout among fine and applied arts trainee instructors in federal colleges of education in South-East, Nigeria. Thereby, educational institutions and government of the study area should collaborate in ensuring that enabling environment is been provided to fine and applied arts trainee instructors in order to limit stress and burnout surrounding the smooth learning of trainee instructors. Finally, fine and applied arts lecturers of the study area is also urged to follow strictly the spelled guidelines on impacting learners of the discipline in order to promote healthy relationship of all trainee instructors..