https://cirdjournals.com/index.php/cldrj/issue/feed 2022-01-29T15:58:32+00:00 CIRD Publication contact@cirdjournals.com Open Journal Systems <p><strong>Clinical Laboratory and Dentistry Research Journal (CLDRJ)</strong> is a peer-reviewed, open-access journal that focuses on the intersection of clinical laboratory science and dentistry. This multidisciplinary journal provides a platform for the dissemination of innovative research, reviews, case studies, and clinical trials that bridge the gap between laboratory findings and dental practice.</p> <p>CLDRJ aims to advance knowledge and practice in the fields of clinical laboratory science and dentistry by publishing high-quality research that: <span style="font-size: 0.875rem;">Enhances diagnostic methods and clinical outcomes in dentistry, </span><span style="font-size: 0.875rem;">Investigates the molecular and cellular mechanisms underlying dental diseases. </span><span style="font-size: 0.875rem;">Develops new biomaterials and technologies for dental applications. </span><span style="font-size: 0.875rem;">Explores the integration of laboratory diagnostics in clinical dental practice.</span></p> <p><span style="font-size: 0.875rem;">CLDRJ boasts a distinguished editorial board comprising leading experts and researchers in clinical laboratory science and dentistry. The editorial board is committed to maintaining the highest standards of scholarly integrity and scientific rigor</span></p> https://cirdjournals.com/index.php/cldrj/article/view/601 2022-01-29T15:58:32+00:00 Clementina Uche Odoh contact@cird.online

<p><em>Cluster of differentiation antigens also known as cluster of differentiation marker[CD marker] are specific type of molecules found on the surface of cell membrane that help differentiate one cell type from another. This is used in identification and characterization of leucocyte cells and other cells that are important to the immune system. Due to the proliferation of many monoclonal antibodies discovered from different laboratories around the world. Their arose the need for harmonization of these monoclonal antibodies used by assigning CD antigens number when two monoclonal antibodies react with a surface antigen. Cluster of differentiation antigens naming system was created after the first international workshop held in paris in 1987, using different monoclonal antibodies, later other international workshop was held in different countries in subsequent years leading to about 391 CD markers. In immuno haematology, diseases such as leukemia, lymphoma, HIV and trasfusion transmitted diseaeses, can be diagnosed and therapy monitored using CD antigens with the method of flow sytometry. Hence much review has to be done to explore its diagnostic and therapeutic use especially during this covid-19 pandemic.</em></p>

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