Why Can'T Be Special Medications For Pneumonia?
Igor Klepikov
MD, Professor,retired
Abstract
Each disease known to modern medicine has its own causes (etiology) and mechanisms of development (pathogenesis). Acute pneumonia (AP) is no exception to this rule. The causes of this disease are known, and among them the most common are bacteria, viruses and fungi. At the same time, for a long period, the leading role was played by the bacterial factor, while viruses were mainly considered as precursors of subsequent microbial aggression, and fungi did not have much epidemiological significance. Not every disease has methods of treating its causes (etiotropic treatment), but for a long time this possibility existed in the AP due to the presence of antibiotics. This type of drug treatment, which can affect bacterial pathogens, had not only positive but also negative consequences, in particular, the development of antibiotic-resistant strains and the impact on the human microbiome with an increase in the number of viral lung lesions. These trends have become particularly noticeable in the past two decades. In addition, the long-term use of antimicrobial drugs has formed an exclusively etiotropic concept of AP, leaving the basics of its pathogenesis without due attention. Attempts to study mechanisms of disease at the cellular and molecular level, to study the effect of pathogens on body tissues, overlooked features of functional disorders of the damaged organ, which distorts the principles of pathogenetic treatment.