http://cirdjournals.com/index.php/iajmcp <p>International Academic Journal of Medical and Clinical Practice (IAJMCP) is a Peer-Reviewed, Open Access Journal that aims to publish Scholarly Articles describing clinical examinations, investigative studies and practices. The journal aims to publish high quality papers in all areas of Medical Science and Clinical Practice. <strong>IAJMCP</strong> publish both traditional full research reports, including short communications and reports/articles on all stages of the research process like study protocols, pilot studies and pre-protocols. <strong>IAJMCP</strong> is novelty attracting, open minded, peer-reviewed medical periodical, designed to serve as a perfectly new platform for both mainstream and new ground shaking works as long as they are technically correct and scientifically motivated.</p> en-US contact@cirdjournals.com (CIRD Publication) contact@cirdjournals.com (CIRD Publication Journals) Wed, 21 Jan 2026 16:27:20 +0000 OJS 3.3.0.7 http://blogs.law.harvard.edu/tech/rss 60 http://cirdjournals.com/index.php/iajmcp/article/view/1429 <p>Ogogoro is a local gin that is consumed indiscriminately in Nigeria and some West African countries. The aim of this study was to investigate selected cardio-inflammatory and oxidative stress biomarkers among ogogoro addicts in Amassoma, Bayelsa State, Nigeria. Three milliliters of blood specimens were withdrawn from each of the 34 participants that constituted this study, with 17 being experimental group and the other 17 being control group, these specimens were dispensed into lithium heparin anti-coagulated bottles respectively. Each of these specimen was spun at 1,500 revolution / minute with the obtained plasma used for the measurement of cardiac biomarkers: troponin-1 (immune-turbidimetry) method and creatinekinase-MB (immune-inhibition) method, inflammatory biomarkers: C-reactive protein (latex turbidimetry) method and interleukin 6 (ELISA) method, oxidative stress biomarkers: malondialdehyde (thiobarbituric acid) method, glutathione peroxidase (immune-inhibitory) method and 8-hydroxy-2-deoxyguanosine (ELISA) method. The data obtained from these measurements were analyzed using SPSS version 23.0 (SPSS Inc., Chicago, IL, USA; version 23.0) while student “t” test was used in comparing the values of the biomarkers between the control and experimental groups with p &lt; 0.05 considered significant. The results revealed significant mean levels elevations in C-reactive protein (p = 0.02), interleukin-6 (p = 0.02), and malondialdehyde (p = 0.01) in the experimental group as compared with that of the control group while there was significant decrease in glutathione peroxidase (p = 0.01) in the experimental group compared with that of the control group. However, the other measured biomarkers: troponin-1 (p = 0.58), creatinekinase-MB (0.62) and 8-hydroxy-2-deoxyguanosine (p = 0.67) revealed no significant alterations in the experimental group when compared with the control group. In conclusion, ogogoro addicts are at the risk of inflammatory and oxidative stress disorders, hence it is recommended that addicts of this local gin should check these biomarkers regularly in any reputable health facility &nbsp;</p> Egoro, E.T, Onyasi, A.A, Eboh, A. Copyright (c) 2026 International Academic Journal of Medical and Clinical Practice http://cirdjournals.com/index.php/iajmcp/article/view/1429 Wed, 21 Jan 2026 00:00:00 +0000